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Teaching
Syllabus for Pharmacology --Back--
（Program for 7-Year Students, School
of Medicine）
Chapter 21 Anti-Angina Pectoris Drugs
1.Objectives
The relationship between anigna with oxygen supply and
demand. The pharmacological effects and clinical uses
of nitrates and β adrenergic blocking drugs.
2.Teaching content
(1)Symptoms and mechanism of angina pectoris.
(2)Nitrates and nitrites: nitroglycerin, isosorbide dinitrate,
pentaerythritol tetranitrate. pharmacological effects:
relaxation of smooth muscle, especially blood vessel smooth
muscle. Decrease preload and afterload, decrease oxygen
consumption. It helps to remove more blood flow from epicardial
area to endocardial area. Opening of the by-pass. Clinical
effects and untoward effects.
(3)βadrenergic blocking drugs: pharmacological effects,
shortcomings and the basis on combination of βblockers
and nitrates.
(4)The pharmacological effects and uses of nimodipine,
diltiazem, prenylamine.
Teaching hours: 3
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