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Teaching
Syllabus for Pharmacology --Back--
（Program for 7-Year Students, School
of Medicine）
Chapter 32 Introduction of chemotherapy
1.Objectives
Chemotherapy usage and brief history of antibacterial
drugs. Commonly used terms for antibacterial drugs and
mechanism of action of antibacterial drugs.
2.Teaching content
Chemotherapy Relationship among chemotherapeutic drugs,
the host and pathogen. Establishment and development of
antibacterialaction.
Commonly used terms: antimicrobial spectrum, resistance
and chemotherapy index .
Bacteria structure and function:
Principle of antibacterialaction:
Inhibition of metabolism of bacterial Folic acid : sulfonamides
and trimethoprim
Effect on synthesis of bacterial cell wall: penicillins
and cephalosporins
Effect on synthesis of bacterial protein: streptomycin,
erythromycin, chloramphenicol and tetracycline.
Effect on function of bacterial cell membrane: polymyxins
nystatin, amphotercin.
Teaching hours: 2
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